Retinal vascular autoregulation in diabetes mellitus.
Publication/Presentation Date
7-1-1982
Abstract
The blue field entoptic technique was used to study autoregulation of the macular retinal circulation in response to acute alterations of intraocular pressure in 71 diabetic eyes and 30 normals matched for age, systemic blood pressure, and ophthalmic artery diastolic pressure. IOPmax, the maximal intraocular pressure at which flow is maintained normal by autoregulation, was normal in eyes with no retinopathy (30 +/- 3.2 mm Hg) but decreased with progression of retinopathy, approaching the resting intraocular pressure in eyes with proliferative retinopathy. The hyperemia observed by normals to an acute reduction of intraocular pressure was not observed frequently in the diabetics with no retinopathy. The frequency of observation of the hyperemia decreased with progression of retinopathy and was uniformly absent in eyes with proliferative retinopathy. A group of eyes with minimal microangiopathy was found to have an abnormal IOPmax and no hyperemic response. The prognostic significance of these parameters remains to be established.
Volume
89
Issue
7
First Page
748
Last Page
750
ISSN
0161-6420
Published In/Presented At
Sinclair, S. H., Grunwald, J. E., Riva, C. E., Braunstein, S. N., Nichols, C. W., & Schwartz, S. S. (1982). Retinal vascular autoregulation in diabetes mellitus. Ophthalmology, 89(7), 748–750. https://doi.org/10.1016/s0161-6420(82)34720-x
Disciplines
Medicine and Health Sciences
PubMedID
7122050
Department(s)
Department of Medicine
Document Type
Article