Disulfiram-like reactions with newer cephalosporins: cefmenoxime.
Publication/Presentation Date
1-1-1984
Abstract
A 54-year-old woman with recurrent adenocarcinoma of the uterus was treated with new third-generation cephalosporin, cefmenoxime, for a urinary tract infection. She received an alcohol-containing tylenol elixir while receiving the drug on two occasions. A disulfiram-like reaction was noticed each time. Such reactions have been described in patients receiving certain drugs such as 5-nitroimidazoles, nitrofurans, sulfonylureas and certain newer cephalosporins with a methyltetrazolethiol side chain. This is the first report of a disulfiram-like reaction with cefmenoxime. The mechanism, causes, and significance of disulfiram-like reactions are discussed.
Volume
287
Issue
2
First Page
45
Last Page
47
ISSN
0002-9629
Published In/Presented At
Kannangara, D. W., Gallagher, K., & Lefrock, J. L. (1984). Disulfiram-like reactions with newer cephalosporins: cefmenoxime. The American journal of the medical sciences, 287(2), 45–47. https://doi.org/10.1097/00000441-198403000-00012
Disciplines
Medicine and Health Sciences
PubMedID
6324592
Department(s)
Department of Medicine
Document Type
Article