Thoracic and pulmonary abnormalities in multiple myeloma. A review of 958 cases.

Publication/Presentation Date

5-1-1978

Abstract

Review of the records of 958 patients with multiple myeloma disclosed thoracic skeletal or pleuropulmonary abnormalities or both in 443 patients (46%). The abnormalities were an initial finding on 25% of the chest roentgenograms. The most common finding, exclusive of plasmacytomas, was thoracic skeletal abnormality in 28% (the initial finding in 15%)--osteolytic lesions being the most frequent abnormality. Localized or diffuse pulmonary infiltrates, most often caused by infections, were present in 10%. Four patients had a diffuse infiltrate thought to be caused by a plasma cell infiltrate (proven in one). In 113 patients, plasmacytomas were seen (intramedullary 102, extramedullary 11)--as an initial finding in 8%. Fifty-eight patients (6%) had pleural effusions. Eight patients with pleural effusion caused by myeloma are added to the eight cases reported in the literature.

Volume

138

Issue

5

First Page

727

Last Page

730

ISSN

0003-9926

Disciplines

Medicine and Health Sciences

PubMedID

646535

Department(s)

Department of Medicine

Document Type

Article

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