A novel, accelerated method of desensitization in a patient with a documented hypersensitivity reaction to clopidogrel.
Publication/Presentation Date
6-1-2010
Abstract
Current standard of care following a percutaneous coronary intervention with stent placement necessitates the use of dual anti-platelet therapy with aspirin and commonly clopidogrel. There is a subset of patients who have a significant clopidogrel allergy and life-threatening hypersensitivity reactions. Desensitization is the process of inducing tolerance to a sensitizing agent via repeated exposure to the agent. There have been previously reported protocols for clopidogrel desensitization. These protocols differ in length and dose escalation and a universally accepted clopidogrel desensitization protocol has yet to be established. We discuss here a novel accelerated approach to clopidogrel desensitization in a patient with a documented hypersensitivity reaction.
Volume
1
Issue
3
First Page
158
Last Page
158
ISSN
1878-5409
Published In/Presented At
Doshi, R., Enoh, A., Antonopoulos, P., & Sattar, P. (2010). A novel, accelerated method of desensitization in a patient with a documented hypersensitivity reaction to clopidogrel. Journal of cardiology cases, 1(3), e158–e160. https://doi.org/10.1016/j.jccase.2009.12.008
Disciplines
Medicine and Health Sciences
PubMedID
30524528
Department(s)
Department of Medicine
Document Type
Article