Nuclear imaging modalities for cardiac amyloidosis.
Publication/Presentation Date
2-1-2014
Abstract
Amyloidosis is a heterogeneous group of diseases characterized by localized or systemic deposition of insoluble extracellular fibrillary proteins in organs and tissues. Several types of amyloid can infiltrate the heart resulting in a restrictive cardiomyopathy, heart failure, and atrial and ventricular arrhythmias. Scintigraphy is a noninvasive method that may facilitate early diagnosis, distinguish various forms of cardiac amyloid, and may be useful in following disease burden. The amyloid-specific tracers presented in this article have been used with planar imaging and/or single-photon emission computed tomography. To date, there are no approved cardiac amyloid tracers although investigational tracers are currently under examination. This article serves to review the current nuclear imaging modalities available in the detection of cardiac amyloid.
Volume
21
Issue
1
First Page
175
Last Page
184
ISSN
1532-6551
Published In/Presented At
Bokhari, Sabahat et al. “Nuclear imaging modalities for cardiac amyloidosis.” Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. 21,1 (2014): 175-84. doi:10.1007/s12350-013-9803-2
Disciplines
Medicine and Health Sciences
PubMedID
24162886
Department(s)
Department of Medicine
Document Type
Article