Left ventricular torsion shear angle volume analysis in patients with hypertension: a global approach for LV diastolic function.
Publication/Presentation Date
9-26-2014
Abstract
BACKGROUND: Torsion shear angle φ is an important measure of left ventricular (LV) systolic and diastolic functions. Here we provide a novel index utilizing LV normalized torsion shear angle φ ^ volume V ^ loop to assess LV diastolic functional properties. We defined the area within φ ^ V ^ loop as torsion hysteresis area, and hypothesized that it may be an important global parameter of diastolic function. We evaluated the φ ^ changes to increased V ^ during early diastole - d φ ^ / d V ^ as a potential measure of LV suction.
METHODS: Sixty resistant hypertension patients (HTN), forty control volunteers were studied using cardiovascular magnetic resonance with tissue tagging. Volumetric and torsional parameters were evaluated.
RESULTS: HTN demonstrated concentric remodeling with preserved ejection fraction. HTN had significantly decreased normalized early filling rate, early diastolic mitral annulus velocity and E/A (1.33 ± 1.13 vs. 2.19 ± 1.07, P < 0.0001) vs. control. Torsion hysteresis area was greater (0.11 ± 0.07 vs. 0.079 ± 0.045, P < 0.001) and peak - d φ ^ / d V ^ at early diastole was higher (10.46 ± 8.51 vs. 6.29 ± 3.85, P = 0.002) than control. Torsion hysteresis area was significantly correlated with E/A (r = -0.23, P = 0.025). Thirteen HTN patients had both E/A ratio < 1.12 (Control mean E/A-1SD) and torsion hysteresis area > 0.12 (Control mean torsion hysteresis area + 1SD).
CONCLUSIONS: Torsion hysteresis area and peak early diastolic - d φ ^ / d V ^ were significantly increased in hypertensive concentric remodeling. The φ ^ V ^ loop takes into account the active and passive recoil processes of LV diastolic and systolic phases, therefore provides a new global description of LV diastolic function.
Volume
16
Issue
1
First Page
70
Last Page
70
ISSN
1532-429X
Published In/Presented At
Schiros, C. G., Desai, R. V., Venkatesh, B. A., Gaddam, K. K., Agarwal, S., Lloyd, S. G., Calhoun, D. A., Denney, T. S., Jr, Dell'italia, L. J., & Gupta, H. (2014). Left ventricular torsion shear angle volume analysis in patients with hypertension: a global approach for LV diastolic function. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 16(1), 70. https://doi.org/10.1186/s12968-014-0070-4
Disciplines
Medicine and Health Sciences
PubMedID
25316384
Department(s)
Department of Medicine
Document Type
Article