Degenerative Mitral Stenosis: Unmet Need for Percutaneous Interventions.
Publication/Presentation Date
4-19-2016
Abstract
Degenerative mitral stenosis (DMS) is an important cause of mitral stenosis, developing secondary to severe mitral annular calcification. With the increase in life expectancy and improved access to health care, more patients with DMS are likely to be encountered in developed nations. These patients are generally elderly with multiple comorbidities and often are high-risk candidates for surgery. The mainstay of therapy in DMS patients is medical management with heart rate control and diuretic therapy. Surgical intervention might be delayed until symptoms are severely limiting and cannot be managed by medical therapy. Mitral valve surgery is also challenging in these patients because of the presence of extensive calcification. Hence, there is a need to develop an alternative percutaneous treatment approach for patients with DMS who are otherwise inoperable or at high risk for surgery. In this review, we summarize the available data on the epidemiology of DMS and diagnostic considerations and current treatment strategies for these patients.
Volume
133
Issue
16
First Page
1594
Last Page
1604
ISSN
1524-4539
Published In/Presented At
Sud, K., Agarwal, S., Parashar, A., Raza, M. Q., Patel, K., Min, D., Rodriguez, L. L., Krishnaswamy, A., Mick, S. L., Gillinov, A. M., Tuzcu, E. M., & Kapadia, S. R. (2016). Degenerative Mitral Stenosis: Unmet Need for Percutaneous Interventions. Circulation, 133(16), 1594–1604. https://doi.org/10.1161/CIRCULATIONAHA.115.020185
Disciplines
Medicine and Health Sciences
PubMedID
27142604
Department(s)
Department of Medicine
Document Type
Article