Acute myeloid leukemia developing in a granulocyte colony-stimulating factor-mobilized stem cell donor: A case report and review of the literature.
Publication/Presentation Date
9-1-2016
Abstract
We describe the first case of a FLT-3 mutated AML in a healthy donor, 3years after recombinant human granulocyte colony stimulating factor (rhG-CSF)-mobilized peripheral blood stem cell (PBSC) harvest. The patient had a myeloablative (MA) matched unrelated donor (MUD) stem cell transplant (SCT) for refractory AML. However, he experienced a secondary graft failure. He had a second non myeloablative (NMA) on day +75 from a second MUD. He achieved a complete neutrophil and platelet engraftment. After 4years of follow up, he is alive in complete remission with full second donor chimerism.
Volume
9
Issue
3
First Page
123
Last Page
125
ISSN
2589-0646
Published In/Presented At
Haddad, H., Wungjiranirun, M., & Gergis, U. (2016). Acute myeloid leukemia developing in a granulocyte colony-stimulating factor-mobilized stem cell donor: A case report and review of the literature. Hematology/oncology and stem cell therapy, 9(3), 123–125. https://doi.org/10.1016/j.hemonc.2015.06.001
Disciplines
Medicine and Health Sciences
PubMedID
26173032
Department(s)
Department of Medicine, Hematology-Medical Oncology Division, Lehigh Valley Topper Cancer Institute
Document Type
Article