Development and Evaluation of a Small Airway Disease Index Derived From Modeling the Late-Expiratory Flattening of the Flow-Volume Loop.
Publication/Presentation Date
1-1-2022
Abstract
Excessive decrease in the flow of the late expiratory portion of a flow volume loop (FVL) or "flattening", reflects small airway dysfunction. The assessment of the flattening is currently determined by visual inspection by the pulmonary function test (PFT) interpreters and is highly variable. In this study, we developed an objective measure to quantify the flattening. We downloaded 172 PFT reports in PDF format from the electronic medical records and digitized and extracted the expiratory portion of the FVL. We located point A (the point of the peak expiratory flow), point B (the point corresponding to 75% of the expiratory vital capacity), and point C (the end of the expiratory portion of the FVL intersecting with the
Volume
13
First Page
914972
Last Page
914972
ISSN
1664-042X
Published In/Presented At
Chen, H., Joshi, S., Oberle, A. J., Wong, A. K., Shaz, D., Thapamagar, S., Tan, L., Anholm, J. D., Giri, P. C., Henriquez, C., & Huang, Y. T. (2022). Development and Evaluation of a Small Airway Disease Index Derived From Modeling the Late-Expiratory Flattening of the Flow-Volume Loop. Frontiers in physiology, 13, 914972. https://doi.org/10.3389/fphys.2022.914972
Disciplines
Medicine and Health Sciences
PubMedID
35733991
Department(s)
Department of Medicine
Document Type
Article
