CHAMPION: CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients

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The objective of the study is to evaluate the safety and efficacy of the Heart Failure Pressure Measurement System in reducing heart failure-related hospitalizations in subjects suffering from heart failure. This will be done using an implanted pressure sensor placed in the subjects pulmonary artery that communicates with an external interrogation device. The external interrogation device can transmit real time pressure measurements to a secure website for the subject’s doctor to review. If for example the pressures are normal, no treatment is needed; however, if the pressures are high, the doctor can increase or adjust the subject’s meds accordingly. In heart failure patients, the pressures are frequently elevated upon arrival and have been so for a period of time. The elevated pressure is relieved by medical therapy. If frequent pressure measurements are taken and trends are reviewed, medications can be adjusted sooner before they reach the point that the patient has to be treated in the hospital for heart failure.


Study completed from December 2008-2001.

Study is published in:

Abraham, W., Adamson, P., Bourge, R., Aaron, M., Costanzo, M., Stevenson, L., & ... Yadav, J. (2011). Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial. Lancet, 377(9766), 658-666. doi:10.1016/S0140-6736(11)60101-3


Cardiology | Health Services Research | Medicine and Health Sciences

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