Leuprolide acetate depot for the treatment of uterine leiomyomas. Changes in bone density, uterine volume and uterine vascular resistive index.

Publication/Presentation Date

9-1-1994

Abstract

This study measured the changes in uterine volume, uterine vascular resistive index and lumbar vertebral bone density before and after a six-month course of leuprolide acetate depot in women with uterine leiomyomas. All nine patients studied were black. The high baseline bone density of black women may provide a greater scope for the use of gonadotropin agonists as compared to women in the general population. A significant reduction in uterine volume was achieved in the patients with leuprolide therapy. Uterine vascular resistive indices were not altered consistently following leuprolide therapy in women with leiomyomas.

Volume

39

Issue

9

First Page

663

Last Page

666

ISSN

0024-7758

Disciplines

Medicine and Health Sciences

PubMedID

7807474

Department(s)

Department of Obstetrics and Gynecology

Document Type

Article

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