Clinical stage I and II endometrial carcinoma treated with surgery and/or radiation therapy: analysis of prognostic and treatment-related factors.
Publication/Presentation Date
6-1-1989
Abstract
This is an analysis of 266 patients with clinical stage I and II endometrial carcinoma treated with curative intent at the University of Florida between October 1964 and December 1980. There was a minimum 5-year follow-up. Thirty-nine patients who died of intercurrent disease less than 5 years from treatment were excluded from analysis of pelvic disease control and determinate disease-free survival. All patients were included in the analysis of complications. Pelvic disease control and determinate disease-free survival rates at 5 years were 91 and 88%, respectively, for stage I and 84 and 68% for stage II. There was no apparent difference in the rates of local control and survival or in the incidence of complications when comparing preoperative with postoperative radiation therapy. Tumor grade, stage, depth of myometrial invasion, and history of exogenous estrogen use or abnormal estrogen balance were of prognostic significance. Data on pelvic disease control, survival, and treatment complications are outlined, and management guidelines are discussed.
Volume
33
Issue
3
First Page
290
Last Page
295
ISSN
0090-8258
Published In/Presented At
Bucy, G. S., Mendenhall, W. M., Morgan, L. S., Chafe, W. E., Wilkinson, E. J., Marcus, R. B., Jr, & Million, R. R. (1989). Clinical stage I and II endometrial carcinoma treated with surgery and/or radiation therapy: analysis of prognostic and treatment-related factors. Gynecologic oncology, 33(3), 290–295. https://doi.org/10.1016/0090-8258(89)90514-3
Disciplines
Medicine and Health Sciences
PubMedID
2722051
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article