Major congenital anomalies in infants and glycosylated hemoglobin levels in insulin-requiring diabetic mothers.
Publication/Presentation Date
1-1-1988
Abstract
Glycosylated hemoglobin levels were obtained in 133 diabetic pregnancies. Nongestational diabetic mothers delivered of infants with major congenital anomalies had significantly higher glycosylated hemoglobin levels than the remaining nongestational diabetic mothers (P less than .001). The higher a mother's glycosylated hemoglobin level, the higher her risk of having a severely affected infant was. The positive predictive value for a nongestational diabetic mother having an infant with severe congenital anomalies was 26% if the glycosylated hemoglobin level was greater than or equal to 11%, 40% if the level was greater than or equal to 12%, and 56% if the level greater than or equal to 13%. However, high glycosylated hemoglobin levels in insulin-requiring gestational diabetic mothers were not predictive of major congenital anomalies.
Volume
8
Issue
4
First Page
309
Last Page
311
ISSN
0743-8346
Published In/Presented At
Rose, B. I., Graff, S., Spencer, R., Hensleigh, P., & Fainstat, T. (1988). Major congenital anomalies in infants and glycosylated hemoglobin levels in insulin-requiring diabetic mothers. Journal of perinatology : official journal of the California Perinatal Association, 8(4), 309–311.
Disciplines
Medicine and Health Sciences
PubMedID
3236099
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article