Antenatal diagnosis and treatment of a fetal goiter.
Publication/Presentation Date
1-1-1980
Abstract
The sonographic diagnosis of a fetal goiter, confirmed at delivery, is described in a fetus exposed to large doses of propylthiouracil, which was administered to the mother. The pregnancy was also complicated by recalcitrant premature labor secondary to polyhydramnios. The intraamniotic instillation of thyroxine decreased the size of the fetal goiter, and numerous therapeutic amniocenteses permitted continuation of the pregnancy, so a mature infant with a goiter but no airway obstruction was delivered. Amniotic fluid reverse-T3 assays confirmed fetal utilization of the thyroxine. Fetal thyroid physiology is discussed briefly along with the benefits of the antenatal sonographic diagnosis of fetal goiter.
Volume
24
Issue
1
First Page
39
Last Page
42
ISSN
0024-7758
Published In/Presented At
Weiner, S., Scharf, J. I., Bolognese, R. J., & Librizzi, R. J. (1980). Antenatal diagnosis and treatment of a fetal goiter. The Journal of reproductive medicine, 24(1), 39–42.
Disciplines
Medicine and Health Sciences
PubMedID
6987398
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article