Comparison of the methods of artificial insemination on the incidence of conception in single unmarried women.
Publication/Presentation Date
1-1-1993
Abstract
OBJECTIVE: To compare pregnancy rates after intrauterine insemination (IUI) versus pericervical insemination in absolute male factor infertility using each patient as her own control.
DESIGN: Ovulatory women with patent fallopian tubes without male partners were alternately inseminated with cryopreserved donor semen using either IUI or pericervical insemination techniques. A total of 81 cycles, which included up to 4 cycles per patient were performed. In this manner a comparison between the efficacy of each method could be evaluated.
SETTING: The donor insemination program at the Center For Assisted Reproduction at Northwestern University Medical School.
PATIENTS: Twenty-six single, healthy, unmarried women with patent fallopian tubes and < 40 years of age without male partners (absolute male factor infertility).
MAIN OUTCOME MEASURES: Positive quantitative serum subunit of human chorionic gonadotropin followed by the presence of an intrauterine gestational sac seen by transvaginal ultrasonography.
RESULTS: Fourteen (54%) of 26 patients conceived including two (14%) miscarriages within four insemination cycles. Seven (17.5%) patients after IUI, and 7 (17.1%) patients after pericervical insemination conceived. The pregnancy rates were similar regardless of the order of insemination method.
CONCLUSION: These findings reveal that there is no statistical difference in the pregnancy outcome between these two methods of insemination in absolute male factor infertility.
Volume
59
Issue
1
First Page
121
Last Page
124
ISSN
0015-0282
Published In/Presented At
Peters, A. J., Hecht, B., Wentz, A. C., & Jeyendran, R. S. (1993). Comparison of the methods of artificial insemination on the incidence of conception in single unmarried women. Fertility and sterility, 59(1), 121–124. https://doi.org/10.1016/s0015-0282(16)55626-x
Disciplines
Medicine and Health Sciences
PubMedID
8419198
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article