Comparison of the methods of artificial insemination on the incidence of conception in single unmarried women.

Publication/Presentation Date

1-1-1993

Abstract

OBJECTIVE: To compare pregnancy rates after intrauterine insemination (IUI) versus pericervical insemination in absolute male factor infertility using each patient as her own control.

DESIGN: Ovulatory women with patent fallopian tubes without male partners were alternately inseminated with cryopreserved donor semen using either IUI or pericervical insemination techniques. A total of 81 cycles, which included up to 4 cycles per patient were performed. In this manner a comparison between the efficacy of each method could be evaluated.

SETTING: The donor insemination program at the Center For Assisted Reproduction at Northwestern University Medical School.

PATIENTS: Twenty-six single, healthy, unmarried women with patent fallopian tubes and < 40 years of age without male partners (absolute male factor infertility).

MAIN OUTCOME MEASURES: Positive quantitative serum subunit of human chorionic gonadotropin followed by the presence of an intrauterine gestational sac seen by transvaginal ultrasonography.

RESULTS: Fourteen (54%) of 26 patients conceived including two (14%) miscarriages within four insemination cycles. Seven (17.5%) patients after IUI, and 7 (17.1%) patients after pericervical insemination conceived. The pregnancy rates were similar regardless of the order of insemination method.

CONCLUSION: These findings reveal that there is no statistical difference in the pregnancy outcome between these two methods of insemination in absolute male factor infertility.

Volume

59

Issue

1

First Page

121

Last Page

124

ISSN

0015-0282

Disciplines

Medicine and Health Sciences

PubMedID

8419198

Department(s)

Department of Obstetrics and Gynecology

Document Type

Article

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