Grey zone score for hypo-osmotic swelling test (HOST) is not associated with embryo implantation defects.
Publication/Presentation Date
1-1-2002
Abstract
PURPOSE: To evaluate the clinical significance of the grey zone range (50-59%) of the hypo-osmotic swelling test (HOST) on sperm samples.
METHODS: Clinical and viable pregnancy rates and implantantion rates following in vitro fertilization-embryo transfer (IVF-ET) were determined in couples where the male partner scored between 50-59% on the HOST. The data were further evaluated according to the discrepancy between viability and HOST. Finally, the study assigned whether treating sperm with the protein digestive enzyme chymotrypsin had any effect on pregnancy outcome.
RESULTS: Pregnancy and implantation rates were comparable for couples with grey zone HOST scores with the normal IVF rate for the center. Having a large discrepancy between viability and HOST scores had no clinical significance nor did treatment with chymotrypsin.
CONCLUSION: In contrast to HOST scores < 50% where extremely poor implantation rates are noted, grey zone scores have no clinical significance.
Volume
29
Issue
1
First Page
25
Last Page
26
ISSN
0390-6663
Published In/Presented At
Check, M. L., Kiefer, D., Check, J. H., Wilson, C., & Katsoff, D. (2002). Grey zone score for hypo-osmotic swelling test (HOST) is not associated with embryo implantation defects. Clinical and experimental obstetrics & gynecology, 29(1), 25–26.
Disciplines
Medicine and Health Sciences
PubMedID
12013086
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article