Multiple primaries among gynecologic malignancies.
Publication/Presentation Date
7-1-1984
Abstract
Seventy-eight synchronous or metachronous tumors among 2362 patients followed by the Downstate Gynecologic Tumor Registry are reviewed. Significant synchronous tumor pairs include cervix (invasive and in situ)-ovary, cervix (in situ)-uterus, cervix (in situ)-kidney, endometrium-ovary, endometrium-rectosigmoid, and ovary-breast. Significant metachronous pairs include cervix (invasive and in situ combined)-lung, cervix (invasive and in situ combined)-upper alimentary tract, and cervix (invasive)-rectosigmoid. In the case of in situ and invasive cervical cancer-lower genital tract, significance was determined for both synchronous and metachronous pairs. Long survival is an important factor in the appearance of a second tumor as demonstrated in patients with cervical carcinoma. Synchronous data prove to be valuable in assessing in risk of second primaries in patients surviving for short periods. The roles of cigarette smoking, hormones, immunosuppression, radiotherapy, and screening are discussed.
Volume
18
Issue
3
First Page
359
Last Page
372
ISSN
0090-8258
Published In/Presented At
Axelrod, J. H., Fruchter, R., & Boyce, J. G. (1984). Multiple primaries among gynecologic malignancies. Gynecologic oncology, 18(3), 359–372. https://doi.org/10.1016/0090-8258(84)90048-9
Disciplines
Medicine and Health Sciences
PubMedID
6745733
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article