Hormonal therapy is associated with a lower prevalence of breast arterial calcification on mammography.

Publication/Presentation Date

6-20-2007

Abstract

OBJECTIVE: To bring further understanding to the relationship between hormonal therapy (HT) and breast arterial calcification (BAC).

METHODS: Of women arriving for breast cancer screening mammography, 1995 consented to complete a survey and have their mammograms analyzed for the presence of BAC. The survey assessed HT use and major risk factors for CAD.

RESULTS: Of the 1919 women with complete data, there were 268 with BAC (14%). When categorized into three age groups, BAC was present in 40.7% of the women > or =65, 10.9% of those 55-64 and 3.0% of thoseor =65 year-old group showed a nearly 50%-point lower prevalence of BAC among HT users compared with women who were not on HT (25.8% versus 74.2%, respectively, p=0.006). With age included as a continuous variable, past use of HT was significantly associated with a lower prevalence of BAC (p

CONCLUSIONS: Well-established cardiovascular risk factors (diabetes, stroke, and age) appear to be associated with a significantly higher incidence of BAC, while HT during the menopausal years appears to be associated with a significantly lower prevalence of BAC.

Volume

57

Issue

2

First Page

154

Last Page

160

ISSN

0378-5122

Disciplines

Medicine and Health Sciences

PubMedID

17289309

Department(s)

Department of Obstetrics and Gynecology

Document Type

Article

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