Oral magnesium for tocolysis: a comparison of magnesium gluconate and enteric-coated magnesium chloride.
Publication/Presentation Date
5-1-1998
Abstract
PURPOSE: Following parenteral magnesium tocolysis for patients in preterm labor. The choice of oral tocolytic medications is controversial.
METHODS: Over a six-month period, 47 patients who were inpreterm labor were randomized after parenteral magnesium tocolysis to receive magnesium gluconate ([Mg-g] 648 mg elemental magnesium/day) or magnesium chloride ([Mg-c] 640 mg elemental magnesium/ day). A serum magnesium was obtained 24 hours after the initiation of oral therapy.
RESULTS: In the 25 patients were treated with Mg-g and 22 with Mg-c there were no differences in patient demographics, initial cervical dilatation hours on parenteral magnesium sulfate, recurrent contractions, or side effects between the two groups. The cost was also similar (Mg-c, $1.40/d; Mg-g, $2.11/d). The serum magnesium levels were higher in the Mg-c group (1.80 +/- 0.28 mg/dl) compared to the Mg-g group (1.63 +/- 0.30 mg/dl) but the difference was not significant.
CONCLUSION: These two preparations of magnesium are similar in their effects on uterine activity and serum levels when used at these dosages.
Volume
39
Issue
5
First Page
180
Last Page
182
ISSN
0026-6396
Published In/Presented At
Martin, R. W., Perry, K. G., Jr, Martin, J. N., Jr, Seago, D. P., Roberts, W. E., & Morrison, J. C. (1998). Oral magnesium for tocolysis: a comparison of magnesium gluconate and enteric-coated magnesium chloride. Journal of the Mississippi State Medical Association, 39(5), 180–182.
Disciplines
Medicine and Health Sciences
PubMedID
9610075
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article