Basal antral follicle number and mean ovarian diameter predict cycle cancellation and ovarian responsiveness in assisted reproductive technology cycles.
Publication/Presentation Date
9-1-2000
Abstract
OBJECTIVE: To determine the predictive value and define threshold levels for basal antral follicle number and mean ovarian diameter in patients undergoing ART cycles.
DESIGN: Retrospective.
SETTING: Tertiary care center.
PATIENTS: Two hundred seventy-eight patients who had ovarian measurements performed on cycle day 3 before beginning treatment with gonadotropins.
INTERVENTION: Pretreatment ovarian ultrasound measurements.
MAIN OUTCOME MEASURE: Number of oocytes retrieved, hormone levels, and cycle outcomes.
RESULTS: A direct linear correlation was observed between mean ovarian diameter and basal follicle number. Both measures demonstrated a positive linear correlation with recovered oocytes, basal E(2), and peak E(2). Both demonstrated a negative linear correlation with ampules of gonadotropins administered, days of stimulation, patient age, cycle day 3 FSH, and FSH:LH ratio. An antral follicle count of
CONCLUSIONS: Ovarian diameter and basal antral follicle number identify patients who may respond poorly to ART stimulation. These ovarian measures correlate well with ART screening and stimulation parameters. This knowledge allows physicians to evaluate and counsel patients immediately before an ART stimulation and to optimize stimulation protocols.
Volume
74
Issue
3
First Page
512
Last Page
517
ISSN
0015-0282
Published In/Presented At
Frattarelli, J. L., Lauria-Costab, D. F., Miller, B. T., Bergh, P. A., & Scott, R. T. (2000). Basal antral follicle number and mean ovarian diameter predict cycle cancellation and ovarian responsiveness in assisted reproductive technology cycles. Fertility and sterility, 74(3), 512–517. https://doi.org/10.1016/s0015-0282(00)00708-1
Disciplines
Medicine and Health Sciences
PubMedID
10973648
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article