Hemostatic imbalances produced by plasma exchange.
Publication/Presentation Date
1-1-1984
Abstract
Ten patients who underwent intensive therapeutic plasma exchange were studied prospectively to determine the nature and extent of changes induced in their coagulation mechanisms. The patients' plasma was replaced with serum albumin and normal saline. Significant changes were noted acutely in the prothrombin time, activated partial thromboplastin time, plasma fibrinogen, and platelet counts. Chronically, significant decreases were found in plasma fibrinogen concentrations and platelet counts. Intensive plasma exchange with fluids devoid of coagulation factors results in defects in the normal hemostatic mechanism.
Volume
24
Issue
4
First Page
336
Last Page
339
ISSN
0041-1132
Published In/Presented At
Domen, R. E., Kennedy, M. S., Jones, L. L., & Senhauser, D. A. (1984). Hemostatic imbalances produced by plasma exchange. Transfusion, 24(4), 336–339. https://doi.org/10.1046/j.1537-2995.1984.24484275577.x
Disciplines
Medicine and Health Sciences
PubMedID
6464159
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article