Case report: ABO discrepancy due to vancomycin complicating a transfusion reaction investigation.
Publication/Presentation Date
1-1-1989
Abstract
A 3-year-old patient with acute myelogenous leukemia developed fever and chills during transfusion of packed red cells. A preliminary workup suggested that a group AB donor unit had been issued to a Group A patient. However, a discrepancy between the ABO group of the original donor unit segment (A) and blood taken from the IV tubing (AB) and the patient's pre- and post-transfusion samples (A and AB, respectively) suggested mother reason for the weak reactivity of some samples with anti-8. The patient's chart revealed that vancomycin, reported to be a cause of non-immune agglutination of red cells, had been injected into the IV tubing one hour prior to transfusion. Further testing confirmed that the patient's febrile response to transfusion was consistent with a nonhemolytic transfusion reaction and was unrelated to the drug-induced, pseudo ABO problem.
Volume
5
Issue
4
First Page
119
Last Page
120
ISSN
0894-203X
Published In/Presented At
Gilbert, D. M., & Domen, R. E. (1989). Case report: ABO discrepancy due to vancomycin complicating a transfusion reaction investigation. Immunohematology, 5(4), 119–120.
Disciplines
Medicine and Health Sciences
PubMedID
15945973
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article