Efficacy of performing red-cell antibody elutions in patients with a positive direct antiglobulin test.
Publication/Presentation Date
1-1-1986
Abstract
Red blood cell antibody elutions are often routinely performed whenever a positive direct antiglobulin test (DAT) is encountered. To evaluate the efficacy of performing routine red-cell elutions we reviewed our antibody elution data. Of 122 eluates, 83 were negative, 35 were warm panagglutinins, 2 were felt to be transfusion-induced alloantibodies, 1 was passively acquired anti-A, and 1 was inconclusive. One of the eluted alloantibodies was not demonstrable in the serum. Thus, only 1 (0.8%) of the eluates provided important information not readily available through serum testing alone. We conclude that extensive serologic evaluation of a positive DAT should be reserved for those patients who have been recently transfused or are suspected of having immune hemolysis.
Volume
51
Issue
4
First Page
324
Last Page
326
ISSN
0042-9007
Published In/Presented At
Domen, R. E., & Grattan, J. (1986). Efficacy of performing red-cell antibody elutions in patients with a positive direct antiglobulin test. Vox sanguinis, 51(4), 324–326. https://doi.org/10.1111/j.1423-0410.1986.tb01978.x
Disciplines
Medicine and Health Sciences
PubMedID
3798867
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article