The number of embryos available for transfer predicts successful pregnancy outcome in women over 39 years with normal ovarian hormonal reserve testing.
Publication/Presentation Date
10-1-2001
Abstract
PURPOSE: The purpose was to determine whether the number of embryos available for transfer following IVF in women over age 39 predicted a successful pregnancy outcome.
METHODS: Retrospective analysis of 455 consecutive IVF cycles in women > or = 40 years of age.
RESULTS: Few cycles were canceled (29/455, 6.4%) or produced no embryos (5/455, 1.1%). Women 40-43 years of age with normal ovarian reserve had a significantly greater delivery rate when > or = 4 embryos were available for transfer than when < 4 embryos were available (17.8% versus 2.4%, P = 0.002). Subsequent IVF cycles, from women with normal FSH whose first cycle produced < 4 embryos, produced delivery rates of 13.0% when > or = 4 embryos were available. Women with abnormal ovarian reserve or age > or = 44 years had very low delivery rates (1.2% and 1.4% respectively).
CONCLUSIONS: The number of embryos available for transfer significantly predicts delivery from IVF-ET among reproductively older women. Many women age 40-43 with normal ovarian reserve can achieve pregnancy through IVF.
Volume
18
Issue
10
First Page
551
Last Page
556
ISSN
1058-0468
Published In/Presented At
Opsahl, M. S., Blauer, K. L., Black, S. H., Lincoln, S. R., Thorsell, L., & Sherins, R. J. (2001). The number of embryos available for transfer predicts successful pregnancy outcome in women over 39 years with normal ovarian hormonal reserve testing. Journal of assisted reproduction and genetics, 18(10), 551–556. https://doi.org/10.1023/a:1011906024170
Disciplines
Medicine and Health Sciences
PubMedID
11699127
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article