Intracranial Myeloid Metaplasia: Diagnosis by CT and Fe52 Scans and Treatment by Cranial Irradiation.
A patient with longstanding agnogenic myeloid metaplasia developed a progressive dementia. CT scanning demonstrated multiple intracranial masses, and a Fe52 bone marrow scan demonstrated erythroid activity within the masses and confirmed the suspicion of extra-medullary hematopoiesis. A potentially hazardous biopsy was avoided, and a course of cranial irradiation was administered, resulting in regression of the masses and clearing of the patient's dementia. Fe52 scintigraphy provides a specific and useful diagnostic approach which may eliminate the need for invasive procedures.
Published In/Presented At
Cornfield, D. B., Shipkin, P., Alavi, A., Becker, J., & Peyster, R. (1983). Intracranial myeloid metaplasia: diagnosis by CT and Fe52 scans and treatment by cranial irradiation. American Journal Of Hematology, 15(3), 273-278.
Medical Pathology | Pathology
Department of Pathology and Laboratory Medicine, Pathology Laboratory Medicine Faculty