Thyroid-Like Follicular Carcinoma of the Kidney.
Publication/Presentation Date
2-1-2017
Abstract
Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare but emerging renal neoplasm that morphologically mimics follicular carcinoma of the thyroid but lacks immunohistochemical expression of thyroid markers such as TTF-1 and thyroglobulin. Here, a case of an incidentally discovered TLFCK in a 27-year-old man is reported. Histologic evaluation demonstrated an encapsulated proliferation of variably sized thyroid follicle-like epithelial-lined spaces filled with colloid-like eosinophilic secretions. Immunohistochemical analysis confirmed lack of expression of the thyroid markers TTF-1 and thyroglobulin with expression of PAX8 and CD10, confirming a neoplasm of renal origin, which correlated to the clinical and radiographic absence of thyroid pathology. In this report, this case is described with an emphasis on the differential diagnosis.
Volume
25
Issue
1
First Page
73
Last Page
77
ISSN
1940-2465
Published In/Presented At
Muscara, M. J., Simper, N. B., & Gandia, E. (2017). Thyroid-Like Follicular Carcinoma of the Kidney. International journal of surgical pathology, 25(1), 73–77. https://doi.org/10.1177/1066896916662153
Disciplines
Medicine and Health Sciences
PubMedID
27474044
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article