Mohs surgery for malignant eccrine neoplasms.
Publication/Presentation Date
12-1-2004
Abstract
BACKGROUND: Eccrine carcinomas (ECs) are rare tumors with potentially aggressive clinical behavior and a high recurrence rate following conventional surgical excision. With the exception of microcystic adnexal carcinoma (MAC), there have been few reports on the use of Mohs micrographic surgery (MMS) as a primary treatment for EC.
OBJECTIVE: To review the use of MMS for EC and compare treatment outcomes with those of conventional surgical excision.
METHODS: We report our use of MMS in 7 cases of EC and review the literature regarding the use of MMS for EC excluding microcystic adnexal carcinoma (MAC), which has been described elsewhere.
RESULTS: A total of 19 case reports describing MMS for non-MAS malignant eccrine neoplasms were reviewed. There were no reported recurrences over an average follow-up period of 29 months, whereas the local recurrence rate following conventional surgical excision of these neoplasms from 10-70%.
CONCLUSIONS: While the clinical experience is limited, the use of MMS appears to decrease recurrence rates when compared to conventional surgical excision. Further experience and longer follow-up intervals will be necessary to demonstrate superior efficacy and recommended surgical margins.
Volume
30
Issue
12 Pt 2
First Page
1574
Last Page
1579
ISSN
1076-0512
Published In/Presented At
Wildemore, J. K., Lee, J. B., & Humphreys, T. R. (2004). Mohs surgery for malignant eccrine neoplasms. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 30(12 Pt 2), 1574–1579. https://doi.org/10.1111/j.1524-4725.2004.30569.x
Disciplines
Medicine and Health Sciences
PubMedID
15606845
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article