Exogenous Ochronosis With Ocular Involvement From Chronic Use of Teavigo.
Publication/Presentation Date
9-1-2023
Abstract
Exogenous ochronosis refers to accumulation of homogentisic acid metabolites in tissues, manifesting as pigmentation of affected tissues. Phenolic compounds are most commonly implicated, including hydroquinone, quinine, phenol, resorcinol, mercury, and picric acid. The affected connective tissues exhibit brownish discoloration when heavily pigmented and the histopathological appearance is characteristic with "banana-shaped" ochre-colored pigment deposits. Herein, the authors describe a rare case of exogenous ochronosis involving the conjunctiva, sclera and skin, as a result of chronic use of Teavigo (94% epigallocatechin gallate), a polyphenol compound with postulated antioxidant and antiapoptotic activity.
Volume
39
Issue
5
First Page
139
Last Page
139
ISSN
1537-2677
Published In/Presented At
Vempuluru, V. S., Laiton, A., Milman, T., Lee, J. B., Eagle, R. C., Jr, & Shields, C. L. (2023). Exogenous Ochronosis With Ocular Involvement From Chronic Use of Teavigo. Ophthalmic plastic and reconstructive surgery, 39(5), e139–e142. https://doi.org/10.1097/IOP.0000000000002395
Disciplines
Medicine and Health Sciences
PubMedID
37010051
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article