An unexpected case of non-uremic calciphylaxis in a patient with multiple risk factors.

Authors

Shannon Nugent
Fred Karaisz
Maisa Elbadawi
Andrew Touati
Neda Nikbakht
Jason B. Lee, MD, Thomas Jefferson UniversityFollow
Hasan Arif

Publication/Presentation Date

12-15-2022

Abstract

A 58-year-old woman with a history of morbid obesity, asthma, and prior warfarin use presented to the hospital with shortness of breath and a three-month history of painful, ulcerated ulcers with retiform purpura of her bilateral distal extremities. A punch biopsy specimen demonstrated focal necrosis and hyalinization of the adipose tissue with subtle arteriolar calcium deposition, findings consistent with calciphylaxis. We discuss the presentation of non-uremic calciphylaxis and review the risk factors, pathophysiology, and interdisciplinary management approach of this rare disease.

Volume

28

Issue

6

ISSN

1087-2108

Published In/Presented At

Nugent, S., Karaisz, F., Elbadawi, M., Touati, A., Nikbakht, N., Lee, J. B., & Arif, H. (2022). An unexpected case of non-uremic calciphylaxis in a patient with multiple risk factors. Dermatology online journal, 28(6), 10.5070/D328659739. https://doi.org/10.5070/D328659739

Disciplines

Medicine and Health Sciences

PubMedID

36809094

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article