A case of multiple myeloma with metachronous chronic myeloid leukemia treated successfully with bortezomib, dexamethasone, and dasatinib.
Publication/Presentation Date
1-1-2014
Abstract
The coexistence of multiple myeloma and chronic myeloid leukemia in a single patient is a very rare event that has been reported very infrequently in the literature. We report a case of a patient who developed chronic myeloid leukemia four years after his diagnosis with multiple myeloma. Historically, no link between the two malignancies has been identified. This synchronous existence complicates the treatment plan for these patients, and there is a lack of evidence on the best therapeutic approach. Our patient was successfully treated with a combination of bortezomib, dexamethasone, and dasatinib, which he tolerated well for eleven months until he eventually succumbed to cardiac complications and pulmonary hypertension leading to his death.
Volume
2014
First Page
962526
Last Page
962526
ISSN
2090-6706
Published In/Presented At
Alsidawi, S., Ghose, A., Qualtieri, J., & Radhakrishnan, N. (2014). A case of multiple myeloma with metachronous chronic myeloid leukemia treated successfully with bortezomib, dexamethasone, and dasatinib. Case reports in oncological medicine, 2014, 962526. https://doi.org/10.1155/2014/962526
PubMedID
25544920
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article