Thalidomide has been advocated as the treatment of choice for recalcitrant aphthae. We describe the case of patient with HIV infection and extensive aphthae whose condition failed to respond to corticosteroids, cyclosporine, and thalidomide. The patient's course was complicated by colonic aphthae. Rapid and sustained resolution was achieved through treatment with granulocyte colony-stimulating factor, a previously unreported therapeutic option.
2 Pt 2
Published In/Presented At
Manders, S. M., Kostman, J. R., Mendez, L., & Russin, V. L. (1995). Thalidomide-resistant HIV-associated aphthae successfully treated with granulocyte colony-stimulating factor. Journal Of The American Academy Of Dermatology, 33(2 Pt 2), 380-382.
Medical Pathology | Pathology
Department of Pathology and Laboratory Medicine, Pathology Laboratory Medicine Faculty