Atypical fibrous histiocytoma of the scrotum.
Publication/Presentation Date
12-1-2003
Abstract
Atypical fibrous histiocytoma is a rare neoplasm. A scrotal location for this tumor is even more unusual. We report a case of a 90-year-old man with scrotal atypical fibrous histiocytoma. Our case had histologic features consistent with those cases previously reported in the literature. The tumor consists of cells with large hyperchromatic irregular nuclei, bizarre multinucleated cells (monster cells), and xanthomatous cells with large prominent nuclei set in a background of classic fibrous histiocytoma. Rare mitotic figures are identified. Immunohistochemical studies showed the tumor cells to be positive for vimentin, smooth muscle actin, desmin, KP-1, factor XIIIa, and MIB-1 (less than 10%). In addition to the expected immunohistochemical studies, the tumor stained diffusely positive for CD117. To our knowledge, this is the first report of atypical fibrous histiocytoma of the scrotum.
Volume
7
Issue
6
First Page
370
Last Page
373
ISSN
1092-9134
Published In/Presented At
Huan, Y., Vapnek, J., & Unger, P. D. (2003). Atypical fibrous histiocytoma of the scrotum. Annals of diagnostic pathology, 7(6), 370–373. https://doi.org/10.1016/j.anndiagpath.2003.09.005
Disciplines
Medicine and Health Sciences
PubMedID
15018121
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article