Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC).

Authors

Yulan Gong
Rajeswari Nagarathinam
Maria F Arisi
Lorenzo Gerratana
Jennifer S Winn
Michael Slifker
Jianming Pei
Kathy Q Cai
Zachary Hasse
Elias Obeid
Julio Noriega
Christopher Sebastiano MD, Lehigh Valley Health NetworkFollow
Eric Ross
Katherine Alpaugh
Massimo Cristofanilli
Sandra V Fernandez

Publication/Presentation Date

8-19-2021

Abstract

To better understand the etiology of inflammatory breast cancer (IBC) and identify potential therapies, we studied genomic alterations in IBC patients. Targeted, next-generation sequencing (NGS) was performed on cell-free DNA (cfDNA) (

Volume

22

Issue

16

ISSN

1422-0067

Published In/Presented At

Gong, Y., Nagarathinam, R., Arisi, M. F., Gerratana, L., Winn, J. S., Slifker, M., Pei, J., Cai, K. Q., Hasse, Z., Obeid, E., Noriega, J., Sebastiano, C., Ross, E., Alpaugh, K., Cristofanilli, M., & Fernandez, S. V. (2021). Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC). International journal of molecular sciences, 22(16), 8924. https://doi.org/10.3390/ijms22168924

Disciplines

Medicine and Health Sciences

PubMedID

34445631

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article