Rosenthal Fibers and Eosinophilic Granular Bodies in a Classic Acoustic Schwannoma.
Publication/Presentation Date
11-1-1997
Abstract
We describe unique features seen in a case of classic acoustic schwannoma. In the central portion of the tumor, abundant Rosenthal fibers and occasional eosinophilic granular bodies were present. Rosenthal fibers are homogeneous eosinophilic structures commonly seen in central nervous system lesions, such as pilocytic astrocytoma, or in the gliotic tissues adjacent to slowly growing neoplasms and some congenital malformations. Eosinophilic granular bodies are also structural markers of slow-growing, well-differentiated neuroglial neoplasms, such as pleomorphic xanthoastrocytoma, ganglion cell tumors, and pilocytic astrocytoma. To the best of our knowledge, however, these two structures have never before been described in schwannomas.
Volume
121
Issue
11
First Page
1207
Last Page
1209
ISSN
0003-9985
Published In/Presented At
Brown DF; Rushing EJ, Archives Of Pathology & Laboratory Medicine [Arch Pathol Lab Med], ISSN: 0003-9985, 1997 Nov; Vol. 121 (11), pp. 1207-1209
Disciplines
Medical Pathology | Pathology
PubMedID
9372750
LVHN link
http://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=9372750&site=ehost-live&scope=site
Department(s)
Department of Pathology and Laboratory Medicine, Pathology Laboratory Medicine Faculty
Document Type
Article