Colon tumor specific nuclear antigen with potential as a pre-tumor diagnostic probe.
Tumor specific nuclear antigen was demonstrated in early stages of chemically-induced colon carcinogenesis. At these early stages, there is no observable nuclear or cytoplasmic alteration in the colon mucosae. The rise in tumor specific nuclear antigen in carcinogen-treated animals can be abolished by simultaneous treatment with carcinogen inhibitor. The potential for tumor specific nuclear antigen to be used as a pretumor diagnostic probe is discussed.
Published In/Presented At
Pumo, D. E., Gootnick, D., Little, B. W., & Chiu, J. F. (1980). Colon tumor specific nuclear antigen with potential as a pre-tumor diagnostic probe. Cancer letters, 9(4), 285–291. https://doi.org/10.1016/0304-3835(80)90019-1
Medicine and Health Sciences
Department of Pathology and Laboratory Medicine