Chromophobe Renal Cell Carcinoma with Sarcomatoid Differentiation.
Publication/Presentation Date
1-1-2023
Abstract
Chromophobe renal cell carcinoma (chRCC) is one of the less common types of kidney cancer and generally portends a more favorable prognosis. RCC with sarcomatoid differentiation has a more aggressive clinical course with poor outcomes. Four cases of chRCC with varying degrees of sarcomatoid differentiation were retrospectively reviewed at our institution, and clinicopathologic data as well as clinical courses were reported. Patients with higher degrees of sarcomatoid differentiation and larger tumors at presentation generally had and worse overall survival. chRCC with sarcomatoid differentiation portends a poor prognosis with limited data on systemic treatment options for metastatic disease.
Volume
10
Issue
3
First Page
1
Last Page
8
ISSN
2203-5826
Published In/Presented At
Lichtbroun, B. J., Shinder, B., Sara, T. G., Srivastava, A., Saraiya, B., Mayer, T. M., Cristelli, R., Sadimin, E., Weiss, R. E., & Singer, E. A. (2023). Chromophobe Renal Cell Carcinoma with Sarcomatoid Differentiation. Journal of kidney cancer and VHL, 10(3), 1–8. https://doi.org/10.15586/jkcvhl.v10i3.254
Disciplines
Medicine and Health Sciences
PubMedID
37441361
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article