Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment.

Publication/Presentation Date

1-1-2011

Abstract

This case report originated from a case of neonatal multisystemic juvenile xanthogranuloma (JXG). The patient presented with blue muffin rush, cervical mass, bone destruction, lung nodule, hepatosplenomegaly, and coagulopathy and was successfully treated with Langerhans cell histiocytosis (LCH) based chemotherapy treatment. Similar cases in literature were reviewed and it seems that JXG, a relatively benign entity, when presented in its systemic form with liver involvement, could have an aggressive course and portend quite poor prognosis. Challenges and special consideration of the diagnosis, treatment, and future case observation are discussed.

Volume

5

First Page

157

Last Page

161

ISSN

1179-5549

Disciplines

Medicine and Health Sciences

PubMedID

21695102

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article

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