Value of postirradiation screening for thyroid nodules. A controlled study of recalled patients.
Publication/Presentation Date
12-14-1979
Abstract
We determined the occurrence of palpable thyroid abnormalities in 214 persons with verified history of head and neck irradiation and in 243 concurrently examined, nonirradiated persons (control subjects). Examinations were performed by two physicians, each unaware of the medical history of the examinees and of the findings of the other examiner. Thyroid nodules, either single or multiple, occurred in 6.1% of irradiated persons and in 4.5% of control subjects (95% confidence interval of the difference, -2.6% to +5.7%). Thyroid enlargement without nodules occurred in 5.6% of irradiated persons and in 3.7% of control subjects (95% confidence interval of the difference, -2.0% to +5.8%). Thyroid cancer was detected in one irradiated and in two nonirradiated persons. Our controlled study did not find an excess number of thyroid abnormalities in previously irradiated subjects.
Volume
242
Issue
24
First Page
2675
Last Page
2678
ISSN
0098-7484
Published In/Presented At
Royce, P. C., MacKay, B. R., & DiSabella, P. M. (1979). Value of postirradiation screening for thyroid nodules. A controlled study of recalled patients. JAMA, 242(24), 2675–2678.
Disciplines
Medicine and Health Sciences
PubMedID
501862
Department(s)
Patient Care Services / Nursing
Document Type
Article