Magnetomotive nanoparticle transducers for optical rheology of viscoelastic materials.

Publication/Presentation Date

12-7-2009

Abstract

The availability of a real-time non-destructive modality to interrogate the mechanical properties of viscoelastic materials would facilitate many new investigations. We introduce a new optical method for measuring elastic properties of samples which employs magnetite nanoparticles as perturbative agents. Magnetic nanoparticles distributed in silicone-based samples are displaced upon probing with a small external magnetic field gradient and depth-resolved optical coherence phase shifts allow for the tracking of scatterers in the sample with nanometer-scale sensitivity. The scatterers undergo underdamped oscillations when the magnetic field is applied step-wise, allowing for the measurement of the natural frequencies of oscillation of the samples. Validation of the measurements is accomplished using a commercial indentation apparatus to determine the elastic moduli of the samples. This real-time non-destructive technique constitutes a novel way of probing the natural frequencies of viscoelastic materials in which magnetic nanoparticles can be introduced.

Volume

17

Issue

25

First Page

23114

Last Page

23122

ISSN

1094-4087

Disciplines

Medicine and Health Sciences | Oncology

PubMedID

20052238

Department(s)

Department of Radiation Oncology

Document Type

Article

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