Whole-abdominal irradiation for the management of gastrointestinal and abdominal manifestations of agnogenic myeloid metaplasia.

Publication/Presentation Date

9-15-1991

Abstract

A patient with a long-standing history of agnogenic myeloid metaplasia developed weight loss and ascites secondary to gastric/small bowel infiltration and peritoneal implants of myeloid tissue. Moderate doses of radiation were very effective in controlling her gastrointestinal symptoms. In contrast to previous reports, clinical improvement after irradiation was a slow, gradual process, requiring 5 months for complete resolution of the patient's ascites. Hematologic suppression may be profound and careful attention to the rate of change in leukocyte and platelet counts is necessary to avoid severe toxicity.

Volume

68

Issue

6

First Page

1251

Last Page

1254

ISSN

0008-543X

Disciplines

Medicine and Health Sciences | Oncology

PubMedID

1873777

Department(s)

Department of Radiation Oncology

Document Type

Article

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