Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy.
BACKGROUND: We focused on a cohort of radiation naïve patients who had recurrent oral cavity cancer (recurrent OCC) to assess their outcomes with salvage multimodal therapy.
METHODS: A retrospective single institutional study was performed of patients with recurrent OCC. Disease recurrence and survival outcomes were assessed.
RESULTS: Seventy-eight patients were analyzed. All patients had salvage surgery and intensity-modulated radiotherapy (IMRT) and 74% had chemotherapy. Five-year overall survival, recurrence-free survival, and locoregional control rates were 59%, 60%, and 74%, respectively.
CONCLUSION: Outcomes of radiation naïve patients with recurrent OCC are fair, and seem similar with patients with locally advanced nonrecurrent OCC treated with multimodal therapy. © 2016 Wiley Periodicals, Inc. Head Neck 39: 633-638, 2017.
Published In/Presented At
Quinlan-Davidson, S. R., Morrison, W. H., Myers, J. N., Gunn, G. B., William, W. N., Jr, Beadle, B. M., Skinner, H. D., Gillenwater, A. M., Frank, S. J., Phan, J., Johnson, F. M., Fuller, C. D., Zafereo, M. E., Rosenthal, D. I., & Garden, A. S. (2017). Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy. Head & neck, 39(4), 633–638. https://doi.org/10.1002/hed.24666
Medicine and Health Sciences | Oncology
Department of Radiation Oncology