A reappraisal of upper gastrointestinal response to low-dose glucagon.
Publication/Presentation Date
1-1-1985
Abstract
Although glucagon is the most commonly used pharmacologic agent for gastrointestinal studies, its exact effects on upper gastrointestinal examinations have not been properly elucidated. A large study by our group did redemonstrate glucagon's significant effect on gastrointestinal motility. However, gastric distention and coating are not improved by glucagon, nor does it have a predictable effect on gastric emptying. Duodenal visualization does appear to be enhanced by the drug. Patient age, weight, and sex are not significant factors in glucagon's response, although they are variables that have an effect on UGI examinations. This article will review physiologic considerations in upper gastrointestinal examinations, with emphasis on glucagon's pharmacodynamics.
Volume
23
Issue
4
First Page
377
Last Page
412
ISSN
1040-8371
Published In/Presented At
Feczko, P. J., Haggar, A. M., & Halpert, R. D. (1985). A reappraisal of upper gastrointestinal response to low-dose glucagon. Critical reviews in diagnostic imaging, 23(4), 377–412.
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
3893892
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article