Disc Degeneration in Unfused Caudal Motion Segments Ten Years Following Surgery for Adolescent Idiopathic Scoliosis.
Publication/Presentation Date
1-1-2018
Abstract
HYPOTHESIS: The frequency of disc degeneration (DD) in the distal mobile segments will increase over time following surgery for adolescent idiopathic scoliosis (AIS).
DESIGN: Retrospective review of a prospective AIS registry.
INTRODUCTION: Durability of surgical outcomes is essential for maintenance of quality of life as well as for family decision making and for assessment of the value of a healthcare intervention. We assessed DD, its risk factors, and association with health-related quality of life 10 years after AIS surgery.
METHODS: Five radiographic indicators of DD, previously validated, were evaluated preoperatively and 1 month, 2, 5, and 10 years postoperatively by a radiologist in operative AIS patients. A composite radiographic score (CRS; range 0-10) was calculated using the sum of each of the DD indicators. The severity of CRS in relation to the time point after surgery and various risk factors were assessed using linear regression or Pearson χ
RESULTS: 193 consecutive patients (mean age at surgery 14.4 years; 86% female) were assessed. Surgical approach included 102 posterior and 91 anterior fusions. Contributors to maximum CRS at 10 years were Schmorl's nodes (7.3% of patients), osteophytes (40.4%), sclerosis (29%), and irregular endplate (8.3%). CRS ≥3 occurred in 1.6%, 0.54%, 3.7%, 6.8%, and 7.3% of patients at the various time points (r
CONCLUSION: In the first study of its kind, we found that only 7.3% of patients had significant DD 10 years after surgical correction of AIS. Rates of DD increased over time. Our data provide evidence to support recommendations to save as many caudal motion segments as possible, to avoid fusing to L4, and maintain the LIV tilt angle below 5° and LIV translation less than 2 cm.
Volume
6
Issue
6
First Page
684
Last Page
690
ISSN
2212-1358
Published In/Presented At
Lonner, B. S., Ren, Y., Upasani, V. V., Marks, M. M., Newton, P. O., Samdani, A. F., Chen, K., Shufflebarger, H. L., Shah, S. A., Lefton, D. R., Nasser, H., Dabrowski, C. T., & Betz, R. R. (2018). Disc Degeneration in Unfused Caudal Motion Segments Ten Years Following Surgery for Adolescent Idiopathic Scoliosis. Spine deformity, 6(6), 684–690. https://doi.org/10.1016/j.jspd.2018.03.013
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
30348344
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article