Parametric imaging using digital subtraction angiography.
Publication/Presentation Date
1-1-1986
Abstract
Digital subtraction angiography following an injection of iodinated contrast material can regularly produce good quality images. In addition to the conventional anatomical information, the timed sequence of digital images also contains useful temporal information which hitherto has been largely ignored. A simple method of image processing is described which utilises this timing information and presents it as a colour-coded set of functional images. Three parameters MAX, T-MAX and T-1/2 MAX are extracted from time-density curves, analogous to the time-activity curves of Nuclear Medicine, on a pixel-by-pixel basis. These parameters are used as a measure of overall organ perfusion, blood transit time between different vascular compartments, and as an indication of the initial delivery of contrast material to an organ. They have found use in the analysis of myocardial perfusion, before and after pharmacological intervention, and in the examination of the cerebral and renal circulations. The potential advantages of this technique derive from its superior spatial, temporal and contrast resolution.
Volume
59
Issue
697
First Page
7
Last Page
11
ISSN
0007-1285
Published In/Presented At
Hunter, G. J., Hunter, J. V., & Brown, N. J. (1986). Parametric imaging using digital subtraction angiography. The British journal of radiology, 59(697), 7–11. https://doi.org/10.1259/0007-1285-59-697-7
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
3512003
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article