Outcome of infants with bronchopulmonary dysplasia who receive extracorporeal membrane oxygenation therapy.
Publication/Presentation Date
10-1-2001
Abstract
BACKGROUND/PURPOSE: Extracorporeal membrane oxygenation (ECMO) is an accepted therapy for acute respiratory failure but more recently has been used in infants with bronchopulmonary dysplasia (BPD) and superimposed acute pulmonary insults. The purpose of this study was to review the outcomes of such infants.
METHODS: Charts of infants at The Children's Hospital of Philadelphia (CHOP) who had a diagnosis of BPD before ECMO were reviewed. In addition, to obtain survival data in a larger population, the Extracorporeal Life Support Organization (ELSO) Registry was searched for infants with BPD before ECMO.
RESULTS: Of 204 patients who received noncardiac ECMO at CHOP, 9 had BPD before ECMO. Of 7 survivors, 4 were still ventilator dependent at 9 to 39 months of corrected age. Developmentally, 4 had significant global delays, whereas 3 had significant language and motor delays with average to mildly delayed cognitive abilities. The ELSO Registry search showed 76 patients with BPD before ECMO, with a 78% survival.
CONCLUSIONS: The survival rate of infants with BPD who receive ECMO is comparable to, or better than, the survival rates in most other ECMO populations. However, there appears to be a high risk of severe pulmonary and neurodevelopmental sequelae.
Volume
36
Issue
10
First Page
1479
Last Page
1484
ISSN
0022-3468
Published In/Presented At
Hibbs, A., Evans, J. R., Gerdes, M., Hunter, J. V., & Cullen, J. A. (2001). Outcome of infants with bronchopulmonary dysplasia who receive extracorporeal membrane oxygenation therapy. Journal of pediatric surgery, 36(10), 1479–1484. https://doi.org/10.1053/jpsu.2001.27026
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
11584392
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article