Magnetization transfer in the investigation of patients with tuberous sclerosis.
Publication/Presentation Date
7-1-1997
Abstract
We examined 21 patients aged 5 months to 19 years, on a 1.5 T magnet. T1-weighted spin-echo images, proton density and T2-weighted images with spin-echo and turbo spin-echo sequences, and contrast-enhanced magnetization transfer (MT) T1-weighted images were obtained in all cases. MT T1-weighted images were performed before injection in 9 patients. Subependymal nodules were found in 14, and cortical and subcortical tubers in 20 of the 21 patients. MT T1-weighted images showed tubers and subependymal nodules as higher signal than normal gray matter and revealed more tubers than conventional sequences in 11 cases. High signal intensity lesions of the white matter were found in 19 patients but were seen only on MT images in 9 cases. When MT images both before and after injection were available, tubers and white matter lesions were more easily recognised on unenhanced MT images because of their higher contrast.
Volume
39
Issue
7
First Page
523
Last Page
528
ISSN
0028-3940
Published In/Presented At
Girard, N., Zimmerman, R. A., Schnur, R. E., Haselgrove, J., & Christensen, K. (1997). Magnetization transfer in the investigation of patients with tuberous sclerosis. Neuroradiology, 39(7), 523–528. https://doi.org/10.1007/s002340050459
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
9258933
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article