Rescue intracranial stenting in acute ischemic stroke: a preliminary Vietnamese study.
Publication/Presentation Date
10-1-2022
Abstract
OBJECTIVE: In cases of acute ischemic stroke (AIS) caused by intracranial large vessel occlusion, rescue intracranial stenting (RIS) has recently emerged as a treatment option for achieving recanalization when mechanical thrombectomy (MT) fails. However, few studies to date have reported on the beneficial outcomes of RIS. Our goal was to analyze whether RIS use can improve prognosis in patients 3 months post-treatment.
PATIENTS AND METHODS: A retrospective analysis was performed on a prospective cohort of patients with AIS treated with RIS at Can Tho S.I.S General Hospital. The study inclusion criteria were evidence of intracranial large vessel occlusion, absence of intracranial hemorrhage (ICH), and severe stenosis or reocclusion after MT. Patients with tandem occlusions, failure to follow up after discharge, or severe or fatal illness concomitant with AIS were excluded from the study. The primary outcome was the "non-poor" prognosis status rate at 3 months after RIS and post-procedural symptomatic ICH (sICH).
RESULTS: The post-treatment outcomes of 85 eligible patients who received RIS between August 2019 and May 2021 were assessed. Of the 85 included patients, 82 (96.5%) achieved successful recanalization, and 4 (4.7%) experienced sICH. At 3-months post-treatment, 47 (55.3%) patients had "non-poor" outcomes, whereas 35 (41.2%) had good outcomes. The use of dual antiplatelet therapy was associated with new infarcts (relative risk [RR]: 0.1; 95% confidence interval [CI]: 0.01-0.7) and sICH occurrence (RR: 0.1; 95% CI: 0.01-0.9).
CONCLUSIONS: Our study suggests that despite the occurrence of post-procedural sICH in a small proportion of cases, RIS could serve as a useful alternative or additional treatment in the event of MT failure.
Volume
26
Issue
19
First Page
6944
Last Page
6952
ISSN
2284-0729
Published In/Presented At
Tran, C. C., Le, M. T., Baxter, B. W., Nguyen-Luu, G., Ngo, M. T., Nguyen-Dao, N. H., Duong-Hoang, L., Mai-Van, M., & Nguyen, M. D. (2022). Rescue intracranial stenting in acute ischemic stroke: a preliminary Vietnamese study. European review for medical and pharmacological sciences, 26(19), 6944–6952. https://doi.org/10.26355/eurrev_202210_29875
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
36263574
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article