A 12-year-old African American girl with subacute bilateral ophthalmoplegia.
Publication/Presentation Date
6-1-2014
Abstract
A twelve-year-old African-American female presented with two week history of progressively worsening headache and fatigue, and vision difficulties for the past week. The physical examination was normal. The neurological evaluation was normal, except for cranial nerves (CN) testing, which showed bilateral restriction of adduction (CN III) and up gaze (CN IV) motions, vertical nystagmus, and left side facial paresis of central origin (CN VII). The bilateral exotropia and ophthalmoplegia are characteristics of WEBINO (Wall-Eyed Bilateral Intranuclear Ophthalmoplegia) syndrome, associated to a brain stem structural lesion. The following causes were evaluated and ruled out: tumor, infection, ischemic stroke, non-infectious inflammation. Pediatric Acquired Demyelinating Syndromes were then considered. Neuromyelitis Optica was ruled out in the absence of neuritis and normal spinal cord MRI. The differential diagnosis between Clinically Isolated Syndrome and Acute Demyelinating Encephalomyelitis, causing an isolated brain stem syndrome, is discussed.
Volume
21
Issue
2
First Page
173
Last Page
176
ISSN
1558-0776
Published In/Presented At
Bar, A., Urbine, J., Bahora, Y., Berkenstock, M., Vodzak, J., Guruprasad, H., Sinha, M., Abed, T., & Legido, A. (2014). A 12-year-old African American girl with subacute bilateral ophthalmoplegia. Seminars in pediatric neurology, 21(2), 173–176. https://doi.org/10.1016/j.spen.2014.04.028
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
25149958
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article