Prognostic value of perihematomal edema area at the initial ED presentation in patients with intracranial hematoma.
Publication/Presentation Date
7-1-2016
Abstract
OBJECTIVE: Intracerebral hemorrhage (ICH) is a potentially life-threatening condition. Interventions and treatments should be managed on time to reduce mortality. It has been put forth that perihematomal edema absolute volume (PHEAV) is related to mortality, however the effect of perihematomal edema absolute area (PHEAA) on mortality is unknown. The objective of this study was to evaluate the effect of PHEAA on 30-day mortality in patients with ICH.
METHODS: Patients were screened with ICD-9, retrospectively. 106 patients were included in the study. Clinical data were obtained from the patient files. Computed tomography (CT) was acquired from the hospital imaging database. PHEAV and PHEAA were measured via CT by two clinicians blinded to the study protocol. The predictors of 30- day mortality were examined.
RESULTS: Forty-three (40.6%) patients died within 30days. Older age, lack of trauma, low Glasgow coma scale and high blood glucose were associated with high mortality (P≤.001). PHEAV and PHEAA values were higher in nonsurvivors (P< .001). PHEAA was detected as an independent predictor of 30-day mortality. The cutoff value of PHEAA for mortality was 33.41cm(2) (sensitivity: 84.4%, specificity: 59.0%). There was no difference between receiver operating characteristic curves of PHEAA and PHEAV (P=.55).
CONCLUSION: In contrast to PHEAV, PHEAA is a simple value which can be measured without the requirement of any additional techniques or extra costs which can be quickly applied and which is an independent indicator of 30-day mortality. PHEAA can accelerate physician interventions for patients with ICH within several hours of ED admission.
Volume
34
Issue
7
First Page
1241
Last Page
1246
ISSN
1532-8171
Published In/Presented At
Ozdinc, S., Unlu, E., Karakaya, Z., Turamanlar, O., Dogan, N., Isler, Y., Gonul, Y., & Boyaci, M. G. (2016). Prognostic value of perihematomal edema area at the initial ED presentation in patients with intracranial hematoma. The American journal of emergency medicine, 34(7), 1241–1246. https://doi.org/10.1016/j.ajem.2016.03.048
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
27085454
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article