Bifocal pineal and suprasellar germinomas with posterior fossa metastases in an adolescent patient.
Publication/Presentation Date
12-1-2022
Abstract
Central nervous system germ cell tumors are rare lesions that are more frequently seen in the pediatric age group. Intracranial germinomas are a type of these germ cell tumors and commonly arise in the pineal region, suprasellar region, or less frequently at both areas (bifocal). Common features of this tumor depend on the location of the lesion(s) and include Parinaud's syndrome, obstructive hydrocephalus, diabetes insipidus, panhypopituitarism, strabismus, and visual acuity defects. We report a case of bifocal pineal and suprasellar germinoma with posterior fossa metastases in a 15-year-old male patient. The involvement of the third ventricular floor and nonthickened inferior pituitary stalk of the suprasellar lesion suggest that it is a metastasis of a primary pineal lesion rather than a dual-primary. This distinction, with the presence of posterior fossa metastases, favors the use of more aggressive treatment with combination radiation therapy and chemotherapy for a better outcome.
Volume
17
Issue
12
First Page
4537
Last Page
4541
ISSN
1930-0433
Published In/Presented At
Kumar, V., Mahdi, E., Moore, N., Vorona, G., Mishra, C., Jones, K., & Urbine, J. (2022). Bifocal pineal and suprasellar germinomas with posterior fossa metastases in an adolescent patient. Radiology case reports, 17(12), 4537–4541. https://doi.org/10.1016/j.radcr.2022.08.102
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
36189158
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article